Guanine deaminase

BE0003061ProteinBacillus subtilis (strain 168)guaD

Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. It is acted on by 1 drug in DrugBank.

Gene name
guaD
UniProtKB entry
O34598Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
156 residues · 17,156 Da
Also known as
3.5.4.3 · GAH · gde · GDEase · Guanine aminohydrolase

Resolves to

Protein
UniProtO34598UniProt nameGUAD_BACSU
Gene
NCBI Gene936695
Pharmacology
KEGGbsu:BSU13170
Structure
PDB1TIYPDB1WKQ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Guanine deaminase, and which indications are they being tested in?

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