Uracil-DNA glycosylase inhibitor

BE0003063ProteinBacteriophage PBS2UGI

This protein binds specifically and reversibly to the host uracil-DNA glycosylase, preventing removal of uracil residues from PBS2 DNA by the host uracil-excision repair system. It is acted on by 1 drug in DrugBank.

Gene name
UGI
UniProtKB entry
P14739Swiss-Prot
Residues / weight
84 residues · 9,476 Da

Resolves to

Protein
UniProtP14739UniProt nameUNGI_BPPB2
Structure
PDB1EUIPDB1LQGPDB1LQM
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Uracil-DNA glycosylase inhibitor, and which indications are they being tested in?

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