Unsaturated glucuronyl hydrolase

BE0003164ProteinBacillus sp. (strain GL1)ugl

Catalyzes the hydrolysis of oligosaccharides with unsaturated glucuronyl residues at the non-reducing terminal, to a sugar or an amino sugar, and an unsaturated D-glucuronic acid (GlcA), which is nonenzymatically converted immediately to alpha-keto acid. It is acted on by 1 drug in DrugBank.

Gene name
ugl
UniProtKB entry
Q9RC92Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
377 residues · 42,861 Da
Also known as
3.2.1.179 · Glycosaminoglycan hydrolase · Glycuronidase · UGL · Unsaturated uronic acid hydrolase

Resolves to

Protein
UniProtQ9RC92UniProt nameUGL_BACGL
Structure
PDB1VD5PDB2AHFPDB2AHG
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Unsaturated glucuronyl hydrolase, and which indications are they being tested in?

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