Orf protein

BE0003165ProteinEscherichia colistx2e B

The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli. It is acted on by 5 drugs in DrugBank.

Gene name
stx2e B
UniProtKB entry
Q47644TrEMBL
Residues / weight
87 residues · 9,650 Da
Also known as
orf · Shiga toxin 2 subunit B · Shiga toxin 2 variant e B-subunit · Shiga toxin 2B subunit · Shiga toxin 2e B

Resolves to

Protein
UniProtQ47644UniProt nameQ47644_ECOLX
Structure
PDB1QOHPDB2BOSPDB4P2C
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Orf protein, and which indications are they being tested in?

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