O-acetyl-ADP-ribose deacetylase

BE0003188ProteinEscherichia coli (strain K12)ymdB

Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate (PubMed:21257746, PubMed:26481419). It is acted on by 1 drug in DrugBank.

Gene name
ymdB
UniProtKB entry
P0A8D6Swiss-Prot
Residues / weight
177 residues · 18,880 Da
Also known as
3.1.1.106 · 3.5.1.- · Regulator of RNase III activity

Resolves to

Protein
UniProtP0A8D6UniProt nameYMDB_ECOLI
Gene
NCBI Gene946987
Pharmacology
KEGGecj:JW1032
Structure
PDB1SPVPDB5CB3PDB5CB5
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on O-acetyl-ADP-ribose deacetylase, and which indications are they being tested in?

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