Lethal(3)malignant brain tumor-like protein 1

BE0003191ProteinHumansL3MBTL1

Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, thereby acting as a 'reader' of a network of post-translational modifications. It is acted on by 1 drug in DrugBank.

Gene name
L3MBTL1
UniProtKB entry
Q9Y468Swiss-Prot
Cellular location
Nucleus
Residues / weight
840 residues · 92,296 Da
Also known as
H-l(3)mbt · H-l(3)mbt protein · KIAA0681 · L(3)mbt protein homolog · L(3)mbt-like

Resolves to

Protein
UniProtQ9Y468UniProt nameLMBL1_HUMAN
Gene
HGNCHGNC:15905NCBI Gene26013GeneCardsL3MBTL1
Pharmacology
KEGGhsa:26013
Structure
PDB1OYXPDB1OZ2PDB1OZ3
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Lethal(3)malignant brain tumor-like protein 1, and which indications are they being tested in?

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