Ribose-5-phosphate isomerase A

BE0003268ProteinHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)rpiA

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. It is acted on by 1 drug in DrugBank.

Gene name
rpiA
UniProtKB entry
P44725Swiss-Prot
Residues / weight
219 residues · 23,093 Da
Also known as
5.3.1.6 · Phosphoriboisomerase A · PRI

Resolves to

Protein
UniProtP44725UniProt nameRPIA_HAEIN
Gene
NCBI Gene949550
Pharmacology
KEGGhin:HI0464
Structure
PDB1M0S
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Ribose-5-phosphate isomerase A, how selective are they, and which programs against it are still in active trials?

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