ADP-ribosylation factor 4

BE0003277ProteinHumansARF4

GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. It is acted on by 1 drug in DrugBank.

Gene name
ARF4
UniProtKB entry
P18085Swiss-Prot
Cellular location
Golgi apparatus
Residues / weight
180 residues · 20,511 Da
Also known as
ARF2

Resolves to

Protein
UniProtP18085UniProt nameARF4_HUMAN
Gene
HGNCHGNC:655NCBI Gene378GeneCardsARF4
Pharmacology
KEGGhsa:378
Structure
PDB1Z6X
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on ADP-ribosylation factor 4, and which indications are they being tested in?

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