GDP-mannose 4,6-dehydratase

BE0003282ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)gmd

Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose. It is acted on by 1 drug in DrugBank.

Gene name
gmd
UniProtKB entry
Q51366Swiss-Prot
Residues / weight
323 residues · 36,399 Da
Also known as
4.2.1.47 · gca · GDP-D-mannose dehydratase

Resolves to

Protein
UniProtQ51366UniProt nameGM4D_PSEAE
Gene
NCBI Gene883089
Pharmacology
KEGGpae:PA5453
Structure
PDB1RPN
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on GDP-mannose 4,6-dehydratase, and which indications are they being tested in?

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