Galactokinase

BE0003295ProteinHumansGALK1

Catalyzes the transfer of a phosphate from ATP to alpha-D-galactose and participates in the first committed step in the catabolism of galactose. It is acted on by 2 drugs in DrugBank.

Gene name
GALK1
UniProtKB entry
P51570Swiss-Prot
Residues / weight
392 residues · 42,272 Da
Also known as
2.7.1.6 · Galactose kinase · GALK

Resolves to

Protein
UniProtP51570UniProt nameGALK1_HUMAN
Gene
HGNCHGNC:4118NCBI Gene2584GeneCardsGALK1
Pharmacology
KEGGhsa:2584
Structure
PDB1WUUPDB6GR2PDB6Q3W
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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1GO termFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Galactokinase, how selective are they, and which programs against it are still in active trials?

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