NimA-related protein

Details

Name
NimA-related protein
Kind
protein
Synonyms
Not Available
Gene Name
Not Available
UniProtKB Entry
Q9RW27TrEMBL
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
NCBI Taxonomy ID
243230
Amino acid sequence
>lcl|BSEQ0019403|NimA-related protein
MSDFYDPRERDPSVSRRPQNRQSDEWIRELLLRGTIARVATLWQGEDGAAFPFITPLAYA
YRPEQGDLVYHTNVVGRLRANAGQGHPATLEVSEIGQFLPSNSPLELSVQYRSVMVFGTA
RVLAGEDARAALTTLSERVFPGLKVGETTRPISEDDLKRTSVYSLSIDRWSGKENWAEQA
IQEEDWPALGPEWLG
Number of residues
195
Molecular Weight
21890.23
Theoretical pI
4.7
GO Classification
Functions
FMN binding / oxidoreductase activity
General Function
Not Available
Specific Function
Not Available
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0019404|NimA-related protein
GTGAGCGACTTCTACGACCCCCGCGAGCGCGACCCGAGTGTCAGCCGTCGCCCACAAAAT
CGCCAGTCCGACGAGTGGATTCGGGAACTGCTGCTGCGCGGCACGATTGCCCGTGTCGCC
ACCCTCTGGCAGGGCGAGGACGGCGCGGCCTTTCCCTTCATCACGCCGCTGGCCTACGCT
TACCGCCCCGAACAGGGCGACCTCGTGTACCACACCAACGTCGTGGGGCGGCTGCGGGCC
AATGCGGGGCAAGGGCACCCGGCCACACTGGAAGTCTCCGAAATCGGCCAGTTTCTGCCG
AGCAACTCGCCGCTCGAACTCAGCGTGCAGTACCGCAGCGTGATGGTCTTTGGCACGGCG
CGGGTGCTGGCGGGCGAGGATGCGCGCGCGGCCCTCACCACCCTCTCCGAGCGGGTGTTC
CCTGGTCTGAAAGTGGGGGAGACGACCCGGCCCATTTCCGAGGATGACCTCAAGCGCACC
AGCGTTTATAGCCTGTCCATTGACCGCTGGAGCGGCAAGGAAAACTGGGCCGAGCAGGCG
ATTCAGGAGGAGGACTGGCCGGCGCTGGGGCCGGAGTGGCTGGGGTAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ9RW27
UniProtKB Entry NameQ9RW27_DEIRA
GenBank Gene IDAE000513
PDB ID(s)1W3O, 1W3P, 1W3Q, 1W3R, 2VPA, 2X1J, 2X1K
KEGG IDdra:DR_0842
NCBI Gene ID1799981
General References
  1. Leiros HK, Kozielski-Stuhrmann S, Kapp U, Terradot L, Leonard GA, McSweeney SM: Structural basis of 5-nitroimidazole antibiotic resistance: the crystal structure of NimA from Deinococcus radiodurans. J Biol Chem. 2004 Dec 31;279(53):55840-9. Epub 2004 Oct 18. [Article]
  2. Leiros HK, Tedesco C, McSweeney SM: High-resolution structure of the antibiotic resistance protein NimA from Deinococcus radiodurans. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jun 1;64(Pt 6):442-7. doi: 10.1107/S1744309108009901. Epub 2008 May 16. [Article]
  3. Leiros HK, Brandsdal BO, McSweeney SM: Biophysical characterization and mutational analysis of the antibiotic resistance protein NimA from Deinococcus radiodurans. Biochim Biophys Acta. 2010 Apr;1804(4):967-76. doi: 10.1016/j.bbapap.2010.01.010. Epub 2010 Jan 21. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Lactic acidapproved, vet_approvedunknowntargetDetails