Voltage-gated potassium channel KCNC4

BE0003319ProteinHumansKCNC4

Voltage-gated potassium channel that opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:7993631). It is acted on by 1 drug in DrugBank.

Gene name
KCNC4
UniProtKB entry
Q03721Swiss-Prot
Cellular location
Membrane
Residues / weight
635 residues · 69,766 Da
Also known as
C1orf30 · KSHIIIC · Potassium voltage-gated channel subfamily C member 4 · Voltage-gated potassium channel subunit Kv3.4

Resolves to

Protein
UniProtQ03721UniProt nameKCNC4_HUMAN
Gene
HGNCHGNC:6236NCBI Gene3749GeneCardsKCNC4
Pharmacology
KEGGhsa:3749
Structure
PDB1B4GPDB1B4IPDB1ZTN
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Voltage-gated potassium channel KCNC4, and which indications are they being tested in?

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