Riboflavin synthase

BE0003327ProteinEscherichia coli (strain K12)ribC

Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. It is acted on by 1 drug in DrugBank.

Gene name
ribC
UniProtKB entry
P0AFU8Swiss-Prot
Residues / weight
213 residues · 23,445 Da
Also known as
2.5.1.9 · ribE · RS

Resolves to

Protein
UniProtP0AFU8UniProt nameRISA_ECOLI
Gene
NCBI Gene945848
Pharmacology
KEGGecj:JW1654
Structure
PDB1HZEPDB1I18PDB1I8D
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Riboflavin synthase, how selective are they, and which programs against it are still in active trials?

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