Riboflavin is a vitamin used to correct vitamin B2 deficiency. Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables.
- Mechanism
- Curator reviewed
Binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide (FAD). The antioxidant activity of riboflavin is principally derived from its role as a precursor of FAD and the role of this cofactor in the production of the antioxidant reduced glutathione. Reduced glutathione is the cofactor of the selenium-containing glutathione peroxidases among other things. The glutathione peroxidases are major antioxidant enzymes. Reduced glutathione is generated by the FAD-containing enzyme glutathione reductase.
- Primary indication
- For the treatment of ariboflavinosis (vitamin B2 deficiency).Curator reviewed · 23 structured indications
- Formula / weight
- C17H20N4O6 · 376.3639 g/mol (avg)
- First approval
- Canada, 1996 · United States, 2015
- Also known as
- Lactoflavin · Lactoflavine · Vitamin B2 · Vitamin Bi · Vitamin G
- Code names
- E101 · INS NO. 101(I) · NCI-0033298 · NSC-33298
- Brand names
Resolves to
AUNGANRZJHBGPY-SCRDCRAPSA-NSMILESCC1=C(C)C=C2N(C[C@H](O)[C@H](O)[C@H](O)CO)C3=NC(=O)NC(=O)C3=NC2=C1What you can answer from here — as of September 23, 2026
Which drugs share a target with Riboflavin, and which of those have an active Phase 3 trial?
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