Metallo-beta-lactamase L1 type 3

BE0003355ProteinPseudomonas maltophilia

Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. It is acted on by 8 drugs in DrugBank.

UniProtKB entry
P52700Swiss-Prot
Cellular location
Periplasm
Residues / weight
290 residues · 30,801 Da
Also known as
3.5.2.6 · B3 metallo-beta-lactamase · Beta-lactamase type II · Beta-lactamase type III · Metallo-beta-lactamase L1

Resolves to

Protein
UniProtP52700UniProt nameBLA1_STEMA
Structure
PDB1SMLPDB2AIOPDB2FM6
Drugs

What you can answer from here — as of May 03, 2025

8DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Metallo-beta-lactamase L1 type 3, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In