Nitrocefin

DB11592ExperimentalSmall molecule

Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin...

Mechanism: Pharmacologically active on Beta-lactamase, Metallo-beta-lactamase L1 type 3, and Beta-lactamase TEM
Curator reviewed
Formula / weight: C₂₁H₁₆N₄O₈S₂ · 516.5 g/mol (avg)

Resolves to

Compound

UNIIEWP54G0J8FCAS41906-86-9ChEMBLCHEMBL480517PubChem6436140

Structure

InChIKeyLHNIIDJCEODSHA-OQRUQETBSA-NSMILES[H][C@]12SCC(\C=C\C3=CC=C(C=C3[N+]([O-])=O)[N+]([O-])=O)=C(N1C(=O)[C@H]2NC(=O)CC1=CC=CS1)C(O)=O

Targets

P00807blaZP00811ampCP52700Metallo-beta-lactamase L1 type 3P62593blaA0A023W3H0OXA-48Q9F663KPC-2Q9EXV5blaUOE-1

What you can answer from here — as of July 10, 2026

7Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

12+ReferencesStructured and connected to the statements they support

Which drugs share a target with Nitrocefin, and which of those have an active Phase 3 trial?

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