Thymidine kinase

BE0003365ProteinHHV-3TK

Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis. It is acted on by 1 drug in DrugBank.

Gene name
TK
UniProtKB entry
P0C0E6Swiss-Prot
Residues / weight
341 residues · 37,843 Da
Also known as
2.7.1.21

Resolves to

Protein
UniProtP0C0E6UniProt nameKITH_VZVO
Structure
PDB1OSN
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thymidine kinase, and which indications are they being tested in?

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