Mitogen-activated protein kinase 13

BE0003391ProteinHumansMAPK13

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. It is acted on by 2 drugs in DrugBank.

Gene name
MAPK13
UniProtKB entry
O15264Swiss-Prot
Residues / weight
365 residues · 42,089 Da
Also known as
2.7.11.24 · MAP kinase 13 · MAP kinase p38 delta · MAPK 13 · Mitogen-activated protein kinase p38 delta

Resolves to

Protein
UniProtO15264UniProt nameMK13_HUMAN
Gene
HGNCHGNC:6875NCBI Gene5603GeneCardsMAPK13
Pharmacology
IUPHAR/GtoPdb1502KEGGhsa:5603
Structure
PDB3COIPDB4EYJPDB4EYM
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Mitogen-activated protein kinase 13, how selective are they, and which programs against it are still in active trials?

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