Neurotrophic factor BDNF precursor form

BE0003394ProteinHumansBDNF

Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678). It is acted on by 4 drugs in DrugBank.

Gene name
BDNF
UniProtKB entry
P23560Swiss-Prot
Cellular location
Secreted
Residues / weight
247 residues · 27,818 Da
Also known as
Abrineurin · Brain-derived neurotrophic factor · proBDNF

Resolves to

Protein
UniProtP23560UniProt nameBDNF_HUMAN
Gene
HGNCHGNC:1033NCBI Gene627GeneCardsBDNF
Pharmacology
KEGGhsa:627
Structure
PDB1B8MPDB1BND
Drugs

What you can answer from here — as of December 03, 2024

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
13Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
15GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
26+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Neurotrophic factor BDNF precursor form, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In