Tubulin beta-2A chain

BE0003400ProteinHumansTUBB2A

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. It is acted on by 4 drugs in DrugBank.

Gene name
TUBB2A
UniProtKB entry
Q13885Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
445 residues · 49,907 Da
Also known as
TUBB2 · Tubulin beta class IIa

Resolves to

Protein
UniProtQ13885UniProt nameTBB2A_HUMAN
Gene
HGNCHGNC:12412NCBI Gene7280GeneCardsTUBB2A
Pharmacology
KEGGhsa:7280
Structure
PDB7NVNPDB8V3OPDB8V3P
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Tubulin beta-2A chain, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In