Insulin-like growth factor 1

BE0003418ProteinHumansIGF1

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. It is acted on by 6 drugs in DrugBank.

Gene name
IGF1
UniProtKB entry
P05019Swiss-Prot
Cellular location
Secreted
Residues / weight
195 residues · 21,841 Da
Also known as
IBP1 · IGF-1 · IGF-I · Insulin-like growth factor I · Mechano growth factor

Resolves to

Protein
UniProtP05019UniProt nameIGF1_HUMAN
Gene
HGNCHGNC:5464NCBI Gene3479GeneCardsIGF1
Pharmacology
KEGGhsa:3479
Structure
PDB1B9GPDB1BQTPDB1GZR
Drugs

What you can answer from here — as of December 03, 2024

6DrugsApproved to experimental, with action, bond type and pharmacological action
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52Clinical trialsTrials of drugs acting on it, by phase and status
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59GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Insulin-like growth factor 1, how selective are they, and which programs against it are still in active trials?

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