Puromycin-sensitive aminopeptidase

BE0003419ProteinHumansNPEPPS

Aminopeptidase with broad substrate specificity for several peptides. It is acted on by 2 drugs in DrugBank.

Gene name
NPEPPS
UniProtKB entry
P55786Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
919 residues · 103,275 Da
Also known as
3.4.11.14 · AAP-S · Cytosol alanyl aminopeptidase · PSA

Resolves to

Protein
UniProtP55786UniProt namePSA_HUMAN
Gene
HGNCHGNC:7900NCBI Gene9520GeneCardsNPEPPS
Pharmacology
IUPHAR/GtoPdb1575KEGGhsa:9520
Structure
PDB8SW0PDB8SW1PDB9O5K
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Puromycin-sensitive aminopeptidase, how selective are they, and which programs against it are still in active trials?

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