Bcl-2-like protein 2

BE0003420ProteinHumansBCL2L2

Promotes cell survival. It is acted on by 4 drugs in DrugBank.

Gene name
BCL2L2
UniProtKB entry
Q92843Swiss-Prot
Cellular location
Mitochondrion membrane
Residues / weight
193 residues · 20,746 Da
Also known as
Apoptosis regulator Bcl-W · Bcl2-L-2 · BCLW · KIAA0271

Resolves to

Protein
UniProtQ92843UniProt nameB2CL2_HUMAN
Gene
HGNCHGNC:42959NCBI Gene599GeneCardsBCL2L2-PABPN1
Pharmacology
IUPHAR/GtoPdb2846KEGGhsa:599
Structure
PDB1MK3PDB1O0LPDB1ZY3
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Bcl-2-like protein 2, and which indications are they being tested in?

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