Far upstream element-binding protein 1

BE0003422ProteinHumansFUBP1

Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. It is acted on by 2 drugs in DrugBank.

Gene name
FUBP1
UniProtKB entry
Q96AE4Swiss-Prot
Cellular location
Nucleus
Residues / weight
644 residues · 67,560 Da
Also known as
DNA helicase V · FBP · FUSE-binding protein 1 · hDH V

Resolves to

Protein
UniProtQ96AE4UniProt nameFUBP1_HUMAN
Gene
HGNCHGNC:4004NCBI Gene8880GeneCardsFUBP1
Pharmacology
KEGGhsa:8880
Structure
PDB1J4WPDB2KXHPDB4LIJ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
18+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Far upstream element-binding protein 1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In