Mesothelin

BE0003459ProteinHumansMSLN

Membrane-anchored forms may play a role in cellular adhesion. It is acted on by 7 drugs in DrugBank.

Gene name
MSLN
UniProtKB entry
Q13421Swiss-Prot
Cellular location
Cell membrane
Residues / weight
622 residues · 68,069 Da
Also known as
CAK1 antigen · MPF · Pre-pro-megakaryocyte-potentiating factor

Resolves to

Protein
UniProtQ13421UniProt nameMSLN_HUMAN
Gene
HGNCHGNC:7371NCBI Gene10232GeneCardsMSLN
Pharmacology
KEGGhsa:10232
Structure
PDB4F3FPDB7U8CPDB7U9J
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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19Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Mesothelin, and which indications are they being tested in?

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