Amatuximab

DB12845InvestigationalProtein Based Therapies

Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.

Mechanism: Pharmacologically active on Mesothelin
Curator reviewed
Also known as: Chimeric monoclonal antibody to mesothelin · Immunoglobulin G1, anti-(mesothelin) (human-mouse monoclonal MORAb-009 heavy chain), disulfide with human-mouse monoclonal MORAb-009 .Kappa.-chain, dimer
Code names: MORAb-009

Resolves to

Compound

UNII6HP0354G04CAS931402-35-6

Targets

Q13421MSLN

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

381Drug interactionsStructured to mechanism, not free text

7Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Amatuximab, and which of those have an active Phase 3 trial?

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