Transcriptional activator Myb

BE0003499ProteinHumansMYB

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. It is acted on by 1 drug in DrugBank.

Gene name
MYB
UniProtKB entry
P10242Swiss-Prot
Cellular location
Nucleus
Residues / weight
640 residues · 72,341 Da
Also known as
Proto-oncogene c-Myb

Resolves to

Protein
UniProtP10242UniProt nameMYB_HUMAN
Gene
HGNCHGNC:7545NCBI Gene4602GeneCardsMYB
Pharmacology
KEGGhsa:4602
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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30GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Transcriptional activator Myb, and which indications are they being tested in?

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