C-C chemokine receptor type 1

BE0003509ProteinHumansCCR1

Chemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses (PubMed:14991608). It is acted on by 5 drugs in DrugBank.

Gene name
CCR1
UniProtKB entry
P32246Swiss-Prot
Cellular location
Cell membrane
Residues / weight
355 residues · 41,172 Da
Also known as
C-C CKR-1 · CC-CKR-1 · CCR-1 · CCR1 · CMKBR1

Resolves to

Protein
UniProtP32246UniProt nameCCR1_HUMAN
Gene
HGNCHGNC:1602NCBI Gene1230GeneCardsCCR1
Pharmacology
IUPHAR/GtoPdb58KEGGhsa:1230
Structure
PDB7VL8PDB7VL9PDB7VLA
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which compounds in development act on C-C chemokine receptor type 1, and which indications are they being tested in?

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