CCX-354

DB12963InvestigationalSmall molecule

CCX354-C has been used in trials studying the treatment of Rheumatoid Arthritis.

Mechanism: Pharmacologically active on C-C chemokine receptor type 1
Curator reviewed
Formula / weight: C₂₂H₂₂ClN₇O₂ · 451.92 g/mol (avg)
Code names: CCX354 · CCX354-C · GSK-2941266

Resolves to

Compound

Structure

InChIKeyZIMLRKWQDLVPEK-UHFFFAOYSA-NSMILESCOC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C2=NC=CN2)C2=CC=CN=C12

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with CCX-354, and which of those have an active Phase 3 trial?

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