Histone deacetylase 7

BE0003525ProteinHumansHDAC7

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
HDAC7
UniProtKB entry
Q8WUI4Swiss-Prot
Cellular location
Nucleus
Residues / weight
952 residues · 102,926 Da
Also known as
3.5.1.98 · HD7 · HD7a · HDAC7A · Histone deacetylase 7A

Resolves to

Protein
UniProtQ8WUI4UniProt nameHDAC7_HUMAN
Gene
HGNCHGNC:14067NCBI Gene51564GeneCardsHDAC7
Pharmacology
IUPHAR/GtoPdb2661KEGGhsa:51564
Structure
PDB3C0YPDB3C0ZPDB3C10
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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24+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Histone deacetylase 7, and which indications are they being tested in?

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