Rho-related GTP-binding protein RhoB

BE0003572ProteinHumansRHOB

Mediates apoptosis in neoplastically transformed cells after DNA damage. It is acted on by 1 drug in DrugBank.

Gene name
RHOB
UniProtKB entry
P62745Swiss-Prot
Cellular location
Late endosome membrane
Residues / weight
196 residues · 22,123 Da
Also known as
3.6.5.2 · ARH6 · ARHB · h6 · Rho cDNA clone 6

Resolves to

Protein
UniProtP62745UniProt nameRHOB_HUMAN
Gene
HGNCHGNC:668NCBI Gene388GenBank36032GeneCardsRHOB
Pharmacology
KEGGhsa:388
Structure
PDB2FV8PDB6HXUPDB6SGE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Rho-related GTP-binding protein RhoB, how selective are they, and which programs against it are still in active trials?

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