A-type voltage-gated potassium channel KCND2

BE0003603ProteinHumansKCND2

Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain. It is acted on by 3 drugs in DrugBank.

Gene name
KCND2
UniProtKB entry
Q9NZV8Swiss-Prot
Cellular location
Cell membrane
Residues / weight
630 residues · 70,536 Da
Also known as
KIAA1044 · Potassium voltage-gated channel subfamily D member 2 · Voltage-gated potassium channel subunit Kv4.2

Resolves to

Protein
UniProtQ9NZV8UniProt nameKCND2_HUMAN
Gene
HGNCHGNC:6238NCBI Gene3751GenBank4530478GeneCardsKCND2
Pharmacology
KEGGhsa:3751
Structure
PDB7E7ZPDB7E83PDB7E84
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on A-type voltage-gated potassium channel KCND2, how selective are they, and which programs against it are still in active trials?

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