DNA polymerase epsilon subunit 4

BE0003616ProteinHumansPOLE4

Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). It is acted on by 1 drug in DrugBank.

Gene name
POLE4
UniProtKB entry
Q9NR33Swiss-Prot
Cellular location
Nucleus
Residues / weight
117 residues · 12,209 Da
Also known as
DNA polymerase epsilon subunit p12 · DNA polymerase II subunit 4

Resolves to

Protein
UniProtQ9NR33UniProt nameDPOE4_HUMAN
Gene
HGNCHGNC:18755NCBI Gene56655GenBank21411517GeneCardsPOLE4
Pharmacology
KEGGhsa:56655
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on DNA polymerase epsilon subunit 4, how selective are they, and which programs against it are still in active trials?

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