DNA polymerase epsilon subunit 3

BE0003617ProteinHumansPOLE3

Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). It is acted on by 1 drug in DrugBank.

Gene name
POLE3
UniProtKB entry
Q9NRF9Swiss-Prot
Cellular location
Nucleus
Residues / weight
147 residues · 16,859 Da
Also known as
Arsenic-transactivated protein · AsTP · CHRAC-17 · CHRAC17 · Chromatin accessibility complex 17 kDa protein

Resolves to

Protein
UniProtQ9NRF9UniProt nameDPOE3_HUMAN
Gene
HGNCHGNC:13546NCBI Gene54107GenBank8100806GeneCardsPOLE3
Pharmacology
KEGGhsa:54107
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
13GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on DNA polymerase epsilon subunit 3, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In