Gastric triacylglycerol lipase

BE0003620ProteinHumansLIPF

Catalyzes the hydrolysis of triacylglycerols to yield free fatty acids, diacylglycerol, monoacylglycerol, and glycerol (PubMed:10358049, PubMed:2243091). It is acted on by 4 drugs in DrugBank.

Gene name
LIPF
UniProtKB entry
P07098Swiss-Prot
Cellular location
Secreted
Residues / weight
398 residues · 45,237 Da
Also known as
3.1.1.3 · Gastric lipase · GL

Resolves to

Protein
UniProtP07098UniProt nameLIPF_HUMAN
Gene
HGNCHGNC:6622NCBI Gene8513GenBank758063GeneCardsLIPF
Pharmacology
KEGGhsa:8513
Structure
PDB1HLG
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Gastric triacylglycerol lipase, how selective are they, and which programs against it are still in active trials?

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