Carbonic anhydrase 5B, mitochondrial

BE0003627ProteinHumansCA5B

Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3. It is acted on by 2 drugs in DrugBank.

Gene name
CA5B
UniProtKB entry
Q9Y2D0Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
317 residues · 36,433 Da
Also known as
4.2.1.1 · CA-VB · Carbonate dehydratase VB · Carbonic anhydrase VB

Resolves to

Protein
UniProtQ9Y2D0UniProt nameCAH5B_HUMAN
Gene
HGNCHGNC:1378NCBI Gene11238GenBank4587223GeneCardsCA5B
Pharmacology
KEGGhsa:11238
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carbonic anhydrase 5B, mitochondrial, how selective are they, and which programs against it are still in active trials?

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