Carbonic anhydrase 13

BE0003633ProteinHumansCA13

Catalyzes the reversible conversion of carbon dioxide to hydrogencarbonate/bicarbonate and thus is essential in the regulation of pH and metabolic processes. It is acted on by 2 drugs in DrugBank.

Gene name
CA13
UniProtKB entry
Q8N1Q1Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
262 residues · 29,443 Da
Also known as
4.2.1.1 · CA-XIII · Carbonate dehydratase XIII · Carbonic anhydrase XIII

Resolves to

Protein
UniProtQ8N1Q1UniProt nameCAH13_HUMAN
Gene
HGNCHGNC:14914NCBI Gene377677GenBank21754549GeneCardsCA13
Pharmacology
KEGGhsa:377677
Structure
PDB3CZVPDB3D0NPDB3DA2
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carbonic anhydrase 13, how selective are they, and which programs against it are still in active trials?

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