Sodium channel regulatory subunit beta-3

BE0003637ProteinHumansSCN3B

Regulatory subunit of multiple voltage-gated sodium (Nav) channels directly mediating the depolarization of excitable membranes. It is acted on by 1 drug in DrugBank.

Gene name
SCN3B
UniProtKB entry
Q9NY72Swiss-Prot
Cellular location
Cell membrane
Residues / weight
215 residues · 24,702 Da
Also known as
KIAA1158

Resolves to

Protein
UniProtQ9NY72UniProt nameSCN3B_HUMAN
Gene
HGNCHGNC:20665NCBI Gene55800GenBank7160975GeneCardsSCN3B
Pharmacology
KEGGhsa:55800
Structure
PDB4L1DPDB7TJ8PDB7TJ9
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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22GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium channel regulatory subunit beta-3, how selective are they, and which programs against it are still in active trials?

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