Copper-transporting ATPase 2

BE0003664ProteinHumansATP7B

Copper ion transmembrane transporter involved in the export of copper out of the cells. It is acted on by 5 drugs in DrugBank.

Gene name
ATP7B
UniProtKB entry
P35670Swiss-Prot
Cellular location
Golgi apparatus, trans-Golgi network membrane
Residues / weight
1,465 residues · 157,261 Da
Also known as
7.2.2.8 · Copper pump 2 · PWD · WC1 · Wilson disease-associated protein

Resolves to

Protein
UniProtP35670UniProt nameATP7B_HUMAN
Gene
HGNCHGNC:870NCBI Gene540GenBank551502GeneCardsATP7B
Pharmacology
KEGGhsa:540
Structure
PDB2ARFPDB2EW9PDB2KOY
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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71+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Copper-transporting ATPase 2, how selective are they, and which programs against it are still in active trials?

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