Solute carrier family 22 member 16

BE0003669ProteinHumansSLC22A16

Facilitative organic cation transporter that mediates the transport of carnitine as well as the polyamine spermidine (PubMed:12089149, PubMed:20037140). It is acted on by 2 drugs in DrugBank.

Gene name
SLC22A16
UniProtKB entry
Q86VW1Swiss-Prot
Cellular location
Cell membrane
Residues / weight
577 residues · 64,614 Da
Also known as
Carnitine transporter 2 · CT2 · Flipt 2 · FLIPT2 · Fly-like putative transporter 2

Resolves to

Protein
UniProtQ86VW1UniProt nameS22AG_HUMAN
Gene
HGNCHGNC:20302NCBI Gene85413GenBank24429900GeneCardsSLC22A16
Pharmacology
KEGGhsa:85413
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 22 member 16, how selective are they, and which programs against it are still in active trials?

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