Large ribosomal subunit protein uL4

BE0003674ProteinEscherichia coli (strain K12)rplD

One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA (PubMed:3298242). It is acted on by 1 drug in DrugBank.

Gene name
rplD
UniProtKB entry
P60723Swiss-Prot
Residues / weight
201 residues · 22,086 Da
Also known as
50S ribosomal protein L4 · eryA

Resolves to

Protein
UniProtP60723UniProt nameRL4_ECOLI
Gene
NCBI Gene31656002GenBank42826
Pharmacology
KEGGecj:JW3281
Structure
PDB2J28PDB2RDOPDB3BBX
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Large ribosomal subunit protein uL4, how selective are they, and which programs against it are still in active trials?

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