Large ribosomal subunit protein bL32

BE0003675ProteinDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)rpmF

Forms a cluster with L17 and L22, and with L22, a pair of 'tweezers' that hold together all the domains of the 23S rRNA. It is acted on by 1 drug in DrugBank.

Gene name
rpmF
UniProtKB entry
P49228Swiss-Prot
Residues / weight
60 residues · 6,792 Da
Also known as
50S ribosomal protein L32

Resolves to

Protein
UniProtP49228UniProt nameRL32_DEIRA
Gene
NCBI Gene1800201GenBank970089
Pharmacology
KEGGdra:DR_2366
Structure
PDB1J5APDB1JZXPDB1JZY
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Large ribosomal subunit protein bL32, how selective are they, and which programs against it are still in active trials?

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