Adenylate cyclase type 2

BE0003732ProteinHumansADCY2

Catalyzes the formation of the signaling molecule cAMP in response to G protein signaling (PubMed:15385642). It is acted on by 3 drugs in DrugBank.

Gene name
ADCY2
UniProtKB entry
Q08462Swiss-Prot
Cellular location
Membrane
Residues / weight
1,091 residues · 123,602 Da
Also known as
4.6.1.1 · Adenylate cyclase type II · Adenylyl cyclase 2 · ATP pyrophosphate-lyase 2 · KIAA1060

Resolves to

Protein
UniProtQ08462UniProt nameADCY2_HUMAN
Gene
HGNCHGNC:233NCBI Gene108GenBank33150814GeneCardsADCY2
Pharmacology
KEGGhsa:108
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Adenylate cyclase type 2, how selective are they, and which programs against it are still in active trials?

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