Adenylate cyclase type 5

BE0003733ProteinHumansADCY5

Catalyzes the formation of the signaling molecule cAMP in response to G protein signaling (PubMed:15385642, PubMed:24700542, PubMed:26206488). It is acted on by 3 drugs in DrugBank.

Gene name
ADCY5
UniProtKB entry
O95622Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,261 residues · 138,906 Da
Also known as
4.6.1.1 · AC5 · Adenylate cyclase type V · Adenylyl cyclase 5 · ATP pyrophosphate-lyase 5

Resolves to

Protein
UniProtO95622UniProt nameADCY5_HUMAN
Gene
HGNCHGNC:236NCBI Gene111GenBank22212711GeneCardsADCY5
Pharmacology
IUPHAR/GtoPdb1282KEGGhsa:111
Structure
PDB8SL3PDB8SL4
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
12+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Adenylate cyclase type 5, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In