Thermolysin

BE0003783ProteinBacillus thermoproteolyticusnpr

Extracellular zinc metalloprotease. It is acted on by 10 drugs in DrugBank.

Gene name
npr
UniProtKB entry
P00800Swiss-Prot
Cellular location
Secreted
Residues / weight
548 residues · 60,104 Da
Also known as
3.4.24.27 · Thermostable neutral proteinase

Resolves to

Protein
UniProtP00800UniProt nameTHER_BACTH
Gene
GenBank441267
Structure
PDB1FJ3PDB1FJOPDB1FJQ
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thermolysin, how selective are they, and which programs against it are still in active trials?

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