Large ribosomal subunit protein uL3

BE0003833ProteinHumansRPL3

Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:32669547, PubMed:35674491). It is acted on by 5 drugs in DrugBank.

Gene name
RPL3
UniProtKB entry
P39023Swiss-Prot
Cellular location
Nucleus, nucleolus
Residues / weight
403 residues · 46,109 Da
Also known as
60S ribosomal protein L3 · HIV-1 TAR RNA-binding protein B · TARBP-B

Resolves to

Protein
UniProtP39023UniProt nameRL3_HUMAN
Gene
HGNCHGNC:10332NCBI Gene6122GenBank313659GeneCardsRPL3
Pharmacology
KEGGhsa:6122
Structure
PDB22TUPDB4UG0PDB4V6X
Drugs

What you can answer from here — as of September 03, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Large ribosomal subunit protein uL3, how selective are they, and which programs against it are still in active trials?

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