Puromycin

DB08437ExperimentalSmall molecule

Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...

Formula / weight: C₂₂H₂₉N₇O₅ · 471.5096 g/mol (avg)
Code names: 3123-L · CL-13900 · P-638

Resolves to

Compound

UNII4A6ZS6Q2CLCAS53-79-2ChEMBLCHEMBL469912ChEBI17939PubChem439530KEGGC01610

Structure

InChIKeyRXWNCPJZOCPEPQ-NVWDDTSBSA-NSMILESCOC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C2N=CN=C3N(C)C)C=C1

Targets

Q96L21RPL10LP40429RPL13AP62829RPL23P61313RPL15P84098RPL19P62750RPL23AQ9UHA3RSL24D1Q9UNX3RPL26L1+5 more

What you can answer from here — as of February 21, 2021

13Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

882Drug interactionsStructured to mechanism, not free text

13+ReferencesStructured and connected to the statements they support

Which drugs share a target with Puromycin, and which of those have an active Phase 3 trial?

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