ATP synthase F(1) complex subunit gamma, mitochondrial

BE0003842ProteinHumansATP5F1C

Subunit gamma, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron... It is acted on by 5 drugs in DrugBank.

Gene name
ATP5F1C
UniProtKB entry
P36542Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
298 residues · 32,996 Da
Also known as
ATP synthase F1 subunit gamma · ATP5C · ATP5C1 · ATP5CL1 · F-ATPase gamma subunit

Resolves to

Protein
UniProtP36542UniProt nameATPG_HUMAN
Gene
HGNCHGNC:833NCBI Gene509GenBank665586GeneCardsATP5F1C
Pharmacology
KEGGhsa:509
Structure
PDB8H9EPDB8H9FPDB8H9I
Drugs

What you can answer from here — as of June 26, 2025

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
7GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
13+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on ATP synthase F(1) complex subunit gamma, mitochondrial, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In