1,2-dihydroxynaphthalene dioxygenase
Details
- Name
- 1,2-dihydroxynaphthalene dioxygenase
- Kind
- protein
- Synonyms
- 1,2-DHN dioxygenase
- 1,2-dihydroxynaphthalene oxygenase
- 1.13.11.56
- Gene Name
- doxG
- UniProtKB Entry
- P0A108Swiss-Prot
- Organism
- Pseudomonas sp. (strain C18)
- NCBI Taxonomy ID
- 69011
- Amino acid sequence
>lcl|BSEQ0012750|1,2-dihydroxynaphthalene dioxygenase MSKQAAVIELGYMGISVKDPDAWKSFATDMLGLQVLDEGEKDRFYLRMDYWHHRIVVHHN GQDDLEYLGWRVAGKPEFEALGQKLIDAGYKIRICDKVEAQERMVLGLMKTEDPGGNPTE IFWGPRIDMSNPFHPGRPLHGKFVTGDQGLGHCIVRQTDVAEAHKFYSLLGFRGDVEYRI PLPNGMTAELSFMHCNARDHSIAFGAMPAAKRLNHLMLEYTHMEDLGYTHQQFVKNEIDI ALQLGIHANDKALTFYGATPSGWLIEPGWRGATAIDEAEYYVGDIFGHGVEATGYGLDVK LS
- Number of residues
- 302
- Molecular Weight
- 33941.375
- Theoretical pI
- 5.83
- GO Classification
- Functionsferrous iron binding / oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenProcessesnaphthalene catabolic process
- General Function
- Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
- Specific Function
- Involved in the naphthalene catabolic pathway. Catalyzes the meta-cleavage of 1,2-dihydroxynaphthalene (1,2-DHN) to yield 2-hydroxychromene-2-carboxylic acid (By similarity).
- Pfam Domain Function
- Glyoxalase (PF00903)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0007565|315 bp ATGACAGTAAAGTGGATTGAAGCAGTCGCTCTTTCTGACATCCTTGAAGGTGACGTCCTC GGCGTGACTGTCGAGGGCAAGGAGCTGGCGCTGTATGAAGTTGAAGGCGAAATCTACGCT ACCGACAACCTGTGCACGCATGGTTCCGCCCGCATGAGTGATGGTTATCTCGAGGGTAGA GAAATCGAATGCCCCTTGCATCAAGGTCGGTTTGACGTTTGCACAGGCAAAGCCCTGTGC GCACCCGTGACACAGAACATCAAAACATATCCAGTCAAGATTGAGAACCTGCGCGTAATG ATTGATTTGAGCTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P0A108 UniProtKB Entry Name NAHC_PSEU8 GenBank Protein ID 294350 GenBank Gene ID M60405 PDB ID(s) 2EHZ, 2EI0, 2EI1, 2EI2, 2EI3 - General References
- Denome SA, Stanley DC, Olson ES, Young KD: Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway. J Bacteriol. 1993 Nov;175(21):6890-901. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details 3,4-Biphenyldiol experimental unknown target Details Biphenyl-2,3-Diol experimental unknown target Details 1,2-Dihydroxynaphthalene experimental unknown target Details