Cytochrome c oxidase subunit 5A, mitochondrial

BE0003988ProteinHumansCOX5A

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 2 drugs in DrugBank.

Gene name
COX5A
UniProtKB entry
P20674Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
150 residues · 16,762 Da
Also known as
Cytochrome c oxidase polypeptide Va

Resolves to

Protein
UniProtP20674UniProt nameCOX5A_HUMAN
Gene
HGNCHGNC:2267NCBI Gene9377GenBank695360GeneCardsCOX5A
Pharmacology
KEGGhsa:9377
Structure
PDB5Z62PDB9I6FPDB9I7U
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Cytochrome c oxidase subunit 5A, mitochondrial, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In